BP897
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 250mg | $900 | Check With Us |
| 500mg | $1400 | Check With Us |
| 1g | $2100 | Check With Us |
: Cat #: V3385 CAS #: 314776-92-6 Purity ≥ 98%
Description: BP 897 is a first potent and selective agonist of dopamine D3 receptor, and a weak antagonist of dopamine D2 receptor with Kis of 0.92 nM and 61 nM for D3 and D2 receptors.
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- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 454.00 |
|---|---|
| Molecular Formula | C26H32ClN3O2 |
| CAS No. | 314776-92-6 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent |
| Protocol | In Vitro | BP 897 hydrochloride has a positive effect on D1 and D4 receptors (Ki=3 μM and 0.3 μM), α1, and α2 adrenergic receptors (Ki=60 nM and 83 nM) and 5HT1A and 5HT7 receptors (Ki=84 nM and 345 nM) have affinity; Affinity for muscarinic receptors, histamine receptors, and opioid receptors is negligible (Ki>1 μM) |
|---|---|---|
| In Vivo | BP 897 hydrochloride binds to D2 receptors in mouse striatum, ED50 It is 15 mg/kg and D3 receptor occupancy is less than 0.5 mg/kg |
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.2026 mL | 11.0132 mL | 22.0264 mL | 44.0529 mL |
| 5mM | 0.4405 mL | 2.2026 mL | 4.4053 mL | 8.8106 mL |
| 10mM | 0.2203 mL | 1.1013 mL | 2.2026 mL | 4.4053 mL |
| 20mM | 0.1101 mL | 0.5507 mL | 1.1013 mL | 2.2026 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.