Maprotiline HCl

This product is for research use only, not for human use. We do not sell to patients.

Maprotiline HCl
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
2g$280Check With Us
5g$520Check With Us
10g$780Check With Us

Cat #: V1116 CAS #: 10347-81-6 Purity ≥ 98%

Description: Maprotiline HCl (Psymion; Ludiomil), the hydrochloride salt of Maprotiline which is a tetracyclic antidepressant, is a selective noradrenalin reuptake inhibitor that has been approved for the treatment of depression.

References: Peng, W.H., et al., Berberine produces antidepressant-like effects in the forced swim test and in the tail suspension test in mice. Life Sci, 2007. 81(11): p. 933-8.

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Product Promise

Promise
Molecular Weight (MW)313.86
Molecular FormulaC20H23N.HCl
CAS No.10347-81-6
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
Solubility In VitroDMSO: 63 mg/mL (200.7 mM)r
Water: <1 mg/mLr
Ethanol: 24 mg/mL (76.5 mM)
SynonymsPsymion; Ludiomil; Maprotilline HCl; Maprotiline Hydrochlorine; Maprotiline Hcl
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM3.1861 mL15.9307 mL31.8613 mL63.7227 mL
5mM0.6372 mL3.1861 mL6.3723 mL12.7445 mL
10mM0.3186 mL1.5931 mL3.1861 mL6.3723 mL
20mM0.1593 mL0.7965 mL1.5931 mL3.1861 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.