L-Adrenaline
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
Size | Price | Stock |
---|---|---|
25g | $450 | Check With Us |
50g | $750 | Check With Us |
100g | $1125 | Check With Us |
Cat #: V1136 CAS #: 51-43-4 Purity ≥ 98%
Description: L-Adrenaline (L-epinephrine; Adrenalin; Levoepinephrine; Epitrate; Lyophrin; Medihaler-Epi), the levo-isomer of adrenaline, belongs to a group of the compounds known as catecholamines.
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- Related Biological Data
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Molecular Weight (MW) | 183.2 |
---|---|
Molecular Formula | C9H13NO3 |
CAS No. | 51-43-4 |
Storage | -20℃ for 3 years in powder formr |
-80℃ for 2 years in solvent | |
Solubility In Vitro | DMSO: 4 mg/mL (21.8 mM)r |
Water: <1 mg/mLr | |
Ethanol: <1 mg/mL | |
Synonyms | L-Adrenaline; Adrenaline; Epinephrine Bitartrate; Epinephrine Hydrochloride; Epinephrine Hydrogen Tartrate; L-epinephrine; Adrenalin; Levoepinephrine; Epitrate; Lyophrin; Medihaler-Epi |
Protocol | In Vivo | Peripheral administration of Prazosin (0, 0.5, 1.0, 1.5 or 2.0 mg/kg; i.p.) can suppress not only central α1-adrenergic-mediated hyperexcitability but also stress-induced anxiety |
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Animal model | Fifty-five alcohol-naive male rats from the 60th generation of selective breeding for alcohol preference | |
Dosages | 0.5, 1.0, 1.5, or 2.0 mg/kg | |
Administration | Injected intraperitoneally (IP); 0.5 mg/mL; once a day at 15 min prior to onset of the daily two hour two-bottle choice, alcohol versus water, access period for two consecutive days and then three weeks later for five consecutive days. |
These protocols are for reference only. InvivoChem does not
independently validate these methods.
Solvent volume to be added | Mass (the weight of a compound) | |||
---|---|---|---|---|
Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
1mM | 5.4585 mL | 27.2926 mL | 54.5852 mL | 109.1703 mL |
5mM | 1.0917 mL | 5.4585 mL | 10.9170 mL | 21.8341 mL |
10mM | 0.5459 mL | 2.7293 mL | 5.4585 mL | 10.9170 mL |
20mM | 0.2729 mL | 1.3646 mL | 2.7293 mL | 5.4585 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.