L-Adrenaline

This product is for research use only, not for human use. We do not sell to patients.

L-Adrenaline
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
25g$450Check With Us
50g$750Check With Us
100g$1125Check With Us

Cat #: V1136 CAS #: 51-43-4 Purity ≥ 98%

Description: L-Adrenaline (L-epinephrine; Adrenalin; Levoepinephrine; Epitrate; Lyophrin; Medihaler-Epi), the levo-isomer of adrenaline, belongs to a group of the compounds known as catecholamines.

References: Dennis D Rasmussen, et al. The alpha1-adrenergic receptor antagonist, prazosin, reduces alcohol drinking in alcohol-preferring (P) rats. Alcohol Clin Exp Res. 2009 Feb;33(2):264-72.

Top Publications Citing Invivochem Products
Publications Citing InvivoChem Products

Product Promise

Promise
Molecular Weight (MW)183.2
Molecular FormulaC9H13NO3
CAS No.51-43-4
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
Solubility In VitroDMSO: 4 mg/mL (21.8 mM)r
Water: <1 mg/mLr
Ethanol: <1 mg/mL
SynonymsL-Adrenaline; Adrenaline; Epinephrine Bitartrate; Epinephrine Hydrochloride; Epinephrine Hydrogen Tartrate; L-epinephrine; Adrenalin; Levoepinephrine; Epitrate; Lyophrin; Medihaler-Epi
ProtocolIn VivoPeripheral administration of Prazosin (0, 0.5, 1.0, 1.5 or 2.0 mg/kg; i.p.) can suppress not only central α1-adrenergic-mediated hyperexcitability but also stress-induced anxiety
Animal modelFifty-five alcohol-naive male rats from the 60th generation of selective breeding for alcohol preference
Dosages0.5, 1.0, 1.5, or 2.0 mg/kg
AdministrationInjected intraperitoneally (IP); 0.5 mg/mL; once a day at 15 min prior to onset of the daily two hour two-bottle choice, alcohol versus water, access period for two consecutive days and then three weeks later for five consecutive days.
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM5.4585 mL27.2926 mL54.5852 mL109.1703 mL
5mM1.0917 mL5.4585 mL10.9170 mL21.8341 mL
10mM0.5459 mL2.7293 mL5.4585 mL10.9170 mL
20mM0.2729 mL1.3646 mL2.7293 mL5.4585 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.