Xylometazoline HCl

This product is for research use only, not for human use. We do not sell to patients.

Xylometazoline HCl
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
10g$450Check With Us
25g$850Check With Us
50g$1275Check With Us

Cat #: V1125 CAS #: 1218-35-5 Purity ≥ 98%

Description: Xylometazoline HCl (xylomethazoline; Otrivine; Amidrin; Balkis; Chlorohist-LA; Decongest; espa-rhin; Gelonasal), the hydrochloride salt of Xylometazoline, is an α-adrenoceptor agonist commonly used as nasal decongestant.

References: Ronald Eccles, et al. The nasal decongestant effect of xylometazoline in the common cold. Am J Rhinol. 2008 Sep-Oct;22(5):491-6.

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Product Promise

Promise
Molecular Weight (MW)280.84
Molecular FormulaC16H24N2.HCl
CAS No.1218-35-5
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
Solubility In VitroDMSO: 27 mg/mL (96.1 mM)r
Water: 56 mg/mL (199.4 mM)r
Ethanol: 56 mg/mL (199.4 mM)
SynonymsTrade name: Otrivine; Amidrin; Balkis; Chlorohist-LA; Decongest; espa-rhin; Gelonasal.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM3.5607 mL17.8037 mL35.6075 mL71.2149 mL
5mM0.7121 mL3.5607 mL7.1215 mL14.2430 mL
10mM0.3561 mL1.7804 mL3.5607 mL7.1215 mL
20mM0.1780 mL0.8902 mL1.7804 mL3.5607 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.