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Tetrahydrozoline HCl (Tetryzoline)

This product is for research use only, not for human use. We do not sell to patients.

Tetrahydrozoline HCl (Tetryzoline)
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Size Price Stock
5g$290Check With Us
10g$480Check With Us
20g$720Check With Us

Cat #: V1150 CAS #: 522-48-5 Purity ≥ 98%

Description: Tetrahydrozoline HCl (Tetryzoline; Tyzanol; Tyzine; Vasopos; Visine) is the hydrochloride salt of terazosin, which is an imidazoline-based alpha adrenergic receptor agonist with antihypertensive activity.

References: Danuta Nowakowska, et al. In vitro effects of vasoconstrictive retraction agents on primary human gingival fibroblasts. Exp Ther Med. 2020 Mar; 19(3): 2037-2044.

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Molecular Weight (MW)236.74
Molecular FormulaC13H16N2.HCl
CAS No.522-48-5
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
Solubility In VitroDMSO: 12 mg/mL (50.7 mM)r
Water: 47 mg/mL (198.5 mM)r
Ethanol: 26 mg/mL (109.8 mM)
SynonymsTetryzoline; Tyzanol; Tyzine; Vasopos; Visine. Tetrahydrozoline HCl, Tetrahydrozoline hydrochloride;
ProtocolIn VitroTetrahydrozoline hydrochloride (0.05% HCl-tetrahydrozoline diluted with DMEM to 1:20 concentration; 24 hours) induces the synthesis of collagen types I and III in primary human gingival fibroblasts
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM4.2240 mL21.1202 mL42.2404 mL84.4809 mL
5mM0.8448 mL4.2240 mL8.4481 mL16.8962 mL
10mM0.4224 mL2.1120 mL4.2240 mL8.4481 mL
20mM0.2112 mL1.0560 mL2.1120 mL4.2240 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.