Phenylephrine HCl

This product is for research use only, not for human use. We do not sell to patients.

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Size	Price	Stock
25g	$350	Check With Us
50g	$600	Check With Us
100g	$900	Check With Us

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Cat #: V1130 CAS #: 61-76-7 Purity ≥ 98%

Description: Phenylephrine HCl (Metaoxedrine chloride; NCIc-55641; NCI c55641; Neosympatol; Oftalfrine; Mezaton; Neo Synephrine; Neo-Synephrine), the hydrochloride salt of Phenylephrine, is a potent and selective α1-adrenergic receptor agonist that is primarily used as a decongestant.

References: Wang J, et al. Phenylephrine promotes cardiac fibroblast proliferation through calcineurin-NFAT pathway. Front Biosci (Landmark Ed). 2016 Jan 1;21:502-13.

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Physicochemical and Storage Information
Protocol
Related Biological Data
Stock Solution Preparation
Quality Control Documentation

Molecular Weight (MW)	203.67
Molecular Formula	C9H13NO2.HCl
CAS No.	61-76-7
Storage	-20℃ for 3 years in powder formr
Storage	-80℃ for 2 years in solvent
Solubility In Vitro	DMSO: 41 mg/mL (201.3 mM)r
	Water: N/Ar
	Ethanol: 41 mg/mL (201.3 mM)
Synonyms	NCI-c55641; Phenylephrine Hydrochloride; Phenylephrine HCl; Metaoxedrine chloride; NCIc55641; NCI c55641; Neosympatol; Oftalfrine; Mezaton; Neo Synephrine; Neo-Synephrine; Neosynephrine ;Phenylephrine; Phenylephrine Hydrochloride; Phenylephrine Tannate;

Protocol	In Vivo	Perfusion of hearts with 100 μM phenylephrine causes a rapid (maximal at 10 min) 12-fold activation of two p38-MAPK isoforms. α1-adrenoceptor agonists such as phenylephrine increase the contractility of the heart. Phenylephrine also activates SAPKs/JNKs in neonatal ventricular myocytes

These protocols are for reference only. InvivoChem does not independently validate these methods.

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	4.9099 mL	24.5495 mL	49.0990 mL	98.1981 mL
5mM	0.9820 mL	4.9099 mL	9.8198 mL	19.6396 mL
10mM	0.4910 mL	2.4550 mL	4.9099 mL	9.8198 mL
20mM	0.2455 mL	1.2275 mL	2.4550 mL	4.9099 mL

Quality Control Documentation	Select Batch Purity ≥ 98% COA MSDS NMR HPLC

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.