Ivabradine D3 HCl

This product is for research use only, not for human use. We do not sell to patients.

For small sizes, please check our retail website as below: www.invivochem.com

Size	Price	Stock
10mg	$850	To Be Confirmed
20mg	$1275	To Be Confirmed
50mg	$2030	To Be Confirmed

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Cat #: V33550 CAS #: 1217809-61-4 Purity ≥ 99%

Description: Ivabradine D3 HCl is the tri-deuterated form and hydrochloride salt of Ivabradine used as an internal standard for the quantification of ivabradine, which is a cardiac pacemaker current (If) inhibitor approved in 2015 for symptomatic management of stable angina pectoris, stable heart-related chest pain and heart failure.

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Molecular Weight (MW)	508.06
Molecular Formula	C27H34D3ClN2O5
CAS No.	1217809-61-4

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	1.9683 mL	9.8414 mL	19.6827 mL	39.3654 mL
5mM	0.3937 mL	1.9683 mL	3.9365 mL	7.8731 mL
10mM	0.1968 mL	0.9841 mL	1.9683 mL	3.9365 mL
20mM	0.0984 mL	0.4921 mL	0.9841 mL	1.9683 mL

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.