Carteolol HCl (OPC-1085 HCl)
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 500mg | $480 | Check With Us |
| 1g | $850 | Check With Us |
| 5g | $2210 | Check With Us |
: Cat #: V1104 CAS #: 51781-21-6 Purity ≥ 98%
Description: Carteolol HCl (OPC1085; Arteoptic; Cartrol; Mikelan; Abbott-43326), the hydrochloride salt of Carteolol, is a potent and non-selective β-adrenoceptor antagonist that was approved for the treatment of glaucoma
Top Publications Citing Invivochem Products
Publications Citing InvivoChem Products
Product Promise
- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 328.83 |
|---|---|
| Molecular Formula | C16H25ClN2O3 |
| CAS No. | 51781-21-6 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: 65 mg/mL (197.7 mM)r |
| Water: <1 mg/mLr | |
| Ethanol: 65 mg/mL (197.7 mM) | |
| Synonyms | OPC 1085; Carteolol Hydrochloride ; Carteolol HCl; OPC-1085; OPC1085; Arteoptic; Cartrol; Mikelan; Abbott-43326; Hydrochloride, Carteolol; Monohydrochloride, Carteolol; |
| Protocol | In Vitro | Carteolol HCl is a beta-adrenergic antagonist used as an anti-arrhythmia agent, an anti-angina agent, an antihypertensive agent, and an antiglaucoma agent. Carteolol hydrochloride at 1 mmol/L (P<0.05) significantly inhibited H2O2-induced cell damage and was able to scavenge O2 (EC50 value: 48 mmol/L). carteolol hydrochloride has a protective action against UVB-induced HCEC damage, and its radical scavenging ability may be an important basis for this effect |
|---|
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 3.0411 mL | 15.2054 mL | 30.4109 mL | 60.8217 mL |
| 5mM | 0.6082 mL | 3.0411 mL | 6.0822 mL | 12.1643 mL |
| 10mM | 0.3041 mL | 1.5205 mL | 3.0411 mL | 6.0822 mL |
| 20mM | 0.1521 mL | 0.7603 mL | 1.5205 mL | 3.0411 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.