Betaxolol HCl (SL75212)
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 500mg | $700 | Check With Us |
| 1g | $1120 | Check With Us |
| 5g | $2800 | Check With Us |
: Cat #: V1106 CAS #: 63659-19-8 Purity ≥ 98%
Description: Betaxolol HCl (Betoptima; Kerlone; Betoptic; Kerlon; SL-75212; ALO-1401-02; ALO140102), the hydrochloride salt of Betaxolol, is a potent beta-1/β1 adrenergic receptor antagonist with antihypertensive effects.
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- Physicochemical and Storage Information
- Protocol
- Related Biological Data
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- Quality Control Documentation
| Molecular Weight (MW) | 343.89 |
|---|---|
| Molecular Formula | C18H29NO3.HCl |
| CAS No. | 63659-19-8 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: 69 mg/mL (200.6 mM)r |
| Water: 69 mg/mL (200.6 mM)r | |
| Ethanol: N/A | |
| Solubility In Vivo | Saline: 30 mg/mL |
| Synonyms | SL-75212 HCl; ALO 140102; SL 75212 HCl; Betaxolol Hydrochloride; Betaxolol HCL; Betoptima; Kerlone; Betoptic; Kerlon; SL75212 HCl; ALO-1401-02; ALO140102 |
| Protocol | In Vitro | Betaxolol hydrochloride is a cardioselective beta-adrenergic receptor blocking agent. |
|---|---|---|
| In Vivo | Betaxolol hydrochloride (5 mg/kg via i.p. injection) was administered at 24 and then 44 h following the final chronic cocaine administration. Animals treated with betaxolol during cocaine withdrawal exhibited a significant attenuation of anxiety-like behavior characterized by increased time spent in the open arms and increased entries into the open arms compared to animals treated with only saline during cocaine withdrawal. Betaxolol hydrochloride did not produce anxiolytic-like effects in control animals treated chronically with saline |
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.9079 mL | 14.5395 mL | 29.0791 mL | 58.1581 mL |
| 5mM | 0.5816 mL | 2.9079 mL | 5.8158 mL | 11.6316 mL |
| 10mM | 0.2908 mL | 1.4540 mL | 2.9079 mL | 5.8158 mL |
| 20mM | 0.1454 mL | 0.7270 mL | 1.4540 mL | 2.9079 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.