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Salmeterol Xinafoate (GR 33343X xinafoate)

This product is for research use only, not for human use. We do not sell to patients.

Salmeterol Xinafoate (GR 33343X xinafoate)
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Size Price Stock
500mg$1020Check With Us
1g$1550Check With Us
5g$4030Check With Us

Cat #: V1101 CAS #: 94749-08-3 Purity ≥ 98%

Description: Salmeterol Xinafoate (GR-33343G, AHR-3929; AH-3923; Salmetedur, Serevent), the Xinafoate salt of Salmeterol, is a potent and long-acting β2-adrenergic receptor agonist with anti-inflammatory effects.

References: Zhiyuan Wang, et al. Efficacy of salmeterol and formoterol combination treatment in mice with chronic obstructive pulmonary disease. Exp Ther Med. 2018 Feb;15(2):1538-1545.

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Molecular Weight (MW)603.75
Molecular FormulaC36H45NO7
CAS No.94749-08-3
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
Solubility In VitroDMSO: 100 mg/mL (165.6 mM)r
Water: <1 mg/mLr
Ethanol: 4 mg/mL (6.6 mM)
SynonymsAHR 3929; AHR-3929; AH-3923; AH3923; Salmeterol xinafoate; GR-33343G, AHR3929; AH 3923; GR-33343X xinafoate; GR 33343X xinafoate; Salmetedur, Serevent®
ProtocolIn VivoSalmeterol (0.16 mg/kg), Formoterol (0.32 mg/kg) and combined treatment have therapeutic effects in mice with chronic obstructive pulmonary disease (COPD)
Animal modelMale C57BL/6 mice (6-8 weeks old, body weight: 32-35 g)
DosagesSalmeterol (0.16 mg/kg) and/or Formoterol (0.32 mg/kg)
AdministrationThe therapeutic efficacy of co-treatment was investigated in this model over a 56-day-long observation period.
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM1.6563 mL8.2816 mL16.5631 mL33.1263 mL
5mM0.3313 mL1.6563 mL3.3126 mL6.6253 mL
10mM0.1656 mL0.8282 mL1.6563 mL3.3126 mL
20mM0.0828 mL0.4141 mL0.8282 mL1.6563 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.