Acebutolol HCl
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 50g | $480 | Check With Us |
| 100g | $800 | Check With Us |
| 200mg | $1200 | Check With Us |
: Cat #: V1109 CAS #: 34381-68-5 Purity ≥ 98%
Description: Acebutolol HCl (Neptal; Prent; Sectral; Dl-Acebutolol), the hydrochloride salt of acebutolol, is a potent antagonist of β-adrenergic receptor with antihypertensive effects.
Top Publications Citing Invivochem Products
Publications Citing InvivoChem Products
Product Promise
- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 372.89 |
|---|---|
| Molecular Formula | C18H28N2O4.HCl |
| CAS No. | 34381-68-5 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: 75 mg/mL (201.1 mM)r |
| Water:r | |
| Ethanol: 75 mg/mL (201.1 mM) | |
| Solubility In Vivo | Saline: 30 mg/mL |
| Synonyms | Acebutolol HCl; Acetobutolol; Neptal; Prent; Sectral; Dl-Acebutolol. |
| Protocol | In Vivo | Acebutolol is a beta blocker for the treatment of hypertension and arrhythmias. Acebutolol following single intravenous administration (10 mg/kg) to rat results in the plasma clearance of 61.9 mL/min/kg, the volume of distribution of 9.6 L/kg, and an elimination half-life of 1.8 hours. Acebutolol following single intravenous administration (50 mg/kg) to rat results in the plasma clearance of 46.5 mL/min/kg, the volume of distribution of 9.5 L/kg, and an elimination half-life of 2.3 hours |
|---|
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.6818 mL | 13.4088 mL | 26.8176 mL | 53.6351 mL |
| 5mM | 0.5364 mL | 2.6818 mL | 5.3635 mL | 10.7270 mL |
| 10mM | 0.2682 mL | 1.3409 mL | 2.6818 mL | 5.3635 mL |
| 20mM | 0.1341 mL | 0.6704 mL | 1.3409 mL | 2.6818 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.