Guanabenz Acetate (BR-750; Wy8678 acetate)
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 1g | $430 | Check With Us |
| 2g | $650 | Check With Us |
| 5g | $980 | Check With Us |
: Cat #: V1151 CAS #: 23256-50-0 Purity ≥ 98%
Description: Guanabenz Acetate (BR-750; Wy-8678; BR 750; Wy 8678; EIPA), the acetate salt of Guanabenz, is an agonist of α2a/b/c-adrenergic receptors with antihypertensive effects.
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- Related Biological Data
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| Molecular Weight (MW) | 291.13 |
|---|---|
| Molecular Formula | C8H8Cl2N4.C2H4O2 |
| CAS No. | 23256-50-0 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: 58 mg/mL (199.2 mM)r |
| Water: <1 mg/mLr | |
| Ethanol: 5 mg/mL (17.2 mM) | |
| Solubility In Vivo | 4% DMSO+30% PEG 300+ddH2O: 5mg/mL |
| Synonyms | BR750; WY-8678, WY 8678, BR-750; Wy-8678; BR 750; Wy 8678; WY-8678 Acetate; WY8678, EIPA |
| Protocol | In Vitro | Guanabenz is an alpha agonist of the alpha-2 type that is used as an antihypertensive drug. It is used to treat high blood pressure (hypertension) |
|---|
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 3.4349 mL | 17.1745 mL | 34.3489 mL | 68.6978 mL |
| 5mM | 0.6870 mL | 3.4349 mL | 6.8698 mL | 13.7396 mL |
| 10mM | 0.3435 mL | 1.7174 mL | 3.4349 mL | 6.8698 mL |
| 20mM | 0.1717 mL | 0.8587 mL | 1.7174 mL | 3.4349 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.