Bambuterol HCl (KWD-2183 HCl)

This product is for research use only, not for human use. We do not sell to patients.

For small sizes, please check our retail website as below: www.invivochem.com

Size	Price	Stock
5g	$750	Check With Us
10g	$1250	Check With Us
20g	$1875	Check With Us

: [email protected] [email protected]

Cat #: V1103 CAS #: 81732-46-9 Purity ≥ 98%

Description: Bambuterol HCl (Bambec; Oxeol; KWD-2183l; UNII-Y1850G1OVC), the hydrochloride salt of Bambuterol which is a prodrug of terbutaline, is a potent and long acting beta-adrenoceptor agonist (LABA) that was approved (outside the US) for use in the treatment of asthma.

Top Publications Citing Invivochem Products

Product Catalog 2022

Guide to Product Handling

Publications Citing InvivoChem Products

Product Promise

Physicochemical and Storage Information
Protocol
Related Biological Data
Stock Solution Preparation
Quality Control Documentation

Molecular Weight (MW)	403.90
Molecular Formula	C18H29N3O5.HCl
CAS No.	81732-46-9
Storage	-20℃ for 3 years in powder formr
Storage	-80℃ for 2 years in solvent
Solubility In Vitro	DMSO: 80 mg/mL (198.1 mM)r
	Water: 72 mg/mL (178.3 mM)r
	Ethanol: 28 mg/mL (69.3 mM)
Synonyms	KWD-2183 HCl; Bambec; Oxeol; KWD2183 HCl; UNII-Y1850G1OVC; KWD 2183 HCl; Bambuterol Hydrochloride; Bambuterol HCl; CHEBI:59167; DSSTox_CID_25515

Protocol	In Vitro	Bambuterol ((±)-Bambuterol hydrochloride; KWD-2183 hydrochloride) is contraindicated in pregnancy and in people with seriously impaired liver function. It can be used by people with renal impairment, but dose adjustments are necessary. The adverse effect profile of bambuterol is similar to that of salbutamol, and may include fatigue, nausea, palpitations, headache, dizziness and tremor.

These protocols are for reference only. InvivoChem does not independently validate these methods.

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	2.4759 mL	12.3793 mL	24.7586 mL	49.5172 mL
5mM	0.4952 mL	2.4759 mL	4.9517 mL	9.9034 mL
10mM	0.2476 mL	1.2379 mL	2.4759 mL	4.9517 mL
20mM	0.1238 mL	0.6190 mL	1.2379 mL	2.4759 mL

Quality Control Documentation	Select Batch Purity ≥ 98% COA MSDS NMR HPLC

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.