Almotriptan Malate (LAS 31416)

This product is for research use only, not for human use. We do not sell to patients.

For small sizes, please check our retail website as below: www.invivochem.com

Size	Price	Stock
500mg	$850	Check With Us
1g	$1350	Check With Us
5g	$3375	Check With Us

: [email protected] [email protected]

Cat #: V1027 CAS #: 181183-52-8 Purity ≥ 98%

Description: Almotriptan Malate (formerly LAS31416; LAS-31416; Almogran; Amignul; Almotrex; Axert), the maleate salt of Almotriptan which is an approved anti-migraine drug, is a potent and selective 5-hydroxytryptamine1B/1D (5-HT1B/1D) receptor agonist.

References: Bou J , et al. Pharmacological characterization of almotriptan: an indolic 5-HT receptor agonist for the treatment of migraine. Eur J Pharmacol, 2000. 410(1): p. 33-41.

Top Publications Citing Invivochem Products

Product Catalog 2022

Guide to Product Handling

Publications Citing InvivoChem Products

Product Promise

Physicochemical and Storage Information
Protocol
Related Biological Data
Stock Solution Preparation
Quality Control Documentation

Molecular Weight (MW)	469.55
Molecular Formula	C17H25N3O2S.C4H6O5
CAS No.	181183-52-8
Storage	-20℃ for 3 years in powder formr
Storage	-80℃ for 2 years in solvent
Solubility In Vitro	DMSO: 94 mg/mL (200.2 mM)r
	Water: <1 mg/mLr
	Ethanol: 53 mg/mL (112.9 mM)
Synonyms	LAS 31416; Almogran; Almotrex; LAS31416; LAS-31416; Amignul; Axert; Almotriptan Malate.

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	2.1297 mL	10.6485 mL	21.2970 mL	42.5940 mL
5mM	0.4259 mL	2.1297 mL	4.2594 mL	8.5188 mL
10mM	0.2130 mL	1.0648 mL	2.1297 mL	4.2594 mL
20mM	0.1065 mL	0.5324 mL	1.0648 mL	2.1297 mL

Quality Control Documentation	Select Batch Purity ≥ 98% COA MSDS NMR HPLC

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.