Buspirone HCl (MJ90221) HCl
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 5g | $480 | Check With Us |
| 10g | $800 | Check With Us |
| 20g | $1200 | Check With Us |
: Cat #: V0971 CAS #: 33386-08-2 Purity ≥ 98%
Description: Buspirone HCl (MJ90221, MJ-90221, Buspar, MJ-9022-1, MJ9022 1, MJ9022-1), the hydrochloride salt of Buspirone which is an azapirone anolog, is a potent serotonergic 5HT1A receptor agonist with anti-psychotic effects.
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- Physicochemical and Storage Information
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- Related Biological Data
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| Molecular Weight (MW) | 421.96 |
|---|---|
| Molecular Formula | C21H31N5O2.HCl |
| CAS No. | 33386-08-2 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: 84 mg/mL (199.1 mM)r |
| Water: 84 mg/mL (199.1 mM)r | |
| Ethanol: 36 mg/mL (85.3 mM) | |
| Solubility In Vivo | 15% Captisol, pH 9: 10 mg/mL |
| SMILES Code | O=C(N(CCCCN1CCN(C2=NC=CC=N2)CC1)C(C3)=O)CC43CCCC4.Cl |
| Synonyms | Buspirone, MJ 9022 1, Buspar, MJ-9022-1, MJ90221, MJ9022 1, MJ9022-1 |
| Protocol | In Vitro | Buspirone hydrochloride (0-400 µg/mL; 6 hours) has cytotoxic effect in Lymphocytes. Buspirone hydrochloride (0-180 µg/mL; 0-3 hours; Lymphocytes) induces ROS formation, MMP collapse, lipid peroxidation, lysosomal damage and elevation of glutathione disulfide (GSSG). |
|---|
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.3699 mL | 11.8495 mL | 23.6989 mL | 47.3979 mL |
| 5mM | 0.4740 mL | 2.3699 mL | 4.7398 mL | 9.4796 mL |
| 10mM | 0.2370 mL | 1.1849 mL | 2.3699 mL | 4.7398 mL |
| 20mM | 0.1185 mL | 0.5925 mL | 1.1849 mL | 2.3699 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.