Ziprasidone HCl (CP-88059)
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 5g | $450 | Check With Us |
| 10g | $850 | Check With Us |
| 20g | $1275 | Check With Us |
: Cat #: V0983 CAS #: 122883-93-6 Purity ≥ 98%
Description: Ziprasidone (CP 88059; CP-88,059; CP-88,059-01; Geodon; Zeldox; Zipwell) HCl, the hydrochloride salt of Ziprasidone, is a novel and potent dopamine and serotonin (5-HT) receptor antagonist with antipsychotic effects.
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- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 449.4 |
|---|---|
| Molecular Formula | C21H21ClN4OS·HCl |
| CAS No. | 122883-93-6 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: 90 mg/mL (200.3 mM)r |
| Water: <1 mg/mLr | |
| Ethanol: <1 mg/mL | |
| SMILES Code | O=C1NC2=C(C=C(CCN3CCN(C4=NSC5=CC=CC=C45)CC3)C(Cl)=C2)C1.[H]Cl |
| Synonyms | CP-88059; CP88059; CP88059 mesylate; Ziprasidone mesylate, CP 88059; CP-88,059; CP-88,059-01; Geodon; Zeldox; Zipwell. |
| Protocol | In Vivo | Ziprasidone hydrochloride (oral gavage; 20 mg/kg; once daily; 7 weeks) results in weight loss, low level physical activity, high resting energy expenditure and greater capacity for thermogenesis when subjected to cold |
|---|---|---|
| Animal model | Eight-week-old female Sprague-Dawley rats weighing 200 to 250 g | |
| Dosages | 20 mg/kg | |
| Administration | Oral gavage; 20 mg/kg; once daily; 7 weeks |
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.2252 mL | 11.1259 mL | 22.2519 mL | 44.5038 mL |
| 5mM | 0.4450 mL | 2.2252 mL | 4.4504 mL | 8.9008 mL |
| 10mM | 0.2225 mL | 1.1126 mL | 2.2252 mL | 4.4504 mL |
| 20mM | 0.1113 mL | 0.5563 mL | 1.1126 mL | 2.2252 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.