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Intepirdine HCl (SB-742457; GSK-742457; RVT-101)

This product is for research use only, not for human use. We do not sell to patients.

Intepirdine HCl (SB-742457; GSK-742457; RVT-101)
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
250mg$750Check With Us
500mg$1250Check With Us
1g$1875Check With Us
email: [email protected]        [email protected]

Cat #: V3647 CAS #: N/A Purity ≥ 99%

Description: Intepirdine HCl (GSK-742457; SB742457; RVT-101), the hydrochloride salt of Intepirdine, is a novel, potent and highly selective 5-HT6 receptor antagonist with pKi of 9.63; it exhibits >100-fold selectivity over other receptors.

References: Neuropharmacology. 2012 Oct;63(5):890-7.; Int J Geriatr Psychiatry. 2011 May;26(5):536-44.

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CAS No.N/A
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The dilution calculator equation
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Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O
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Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.