VUF 10166

This product is for research use only, not for human use. We do not sell to patients.

VUF 10166
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
250mg$699Check With Us
500mg$1139Check With Us
1g$1710Check With Us

Cat #: V1026 CAS #: 155584-74-0 Purity ≥ 98%

Description: VUF10166 (VUF-10166; VUF 10166) is a novel, potent and competitive antagonist against serotonin 5-HT3A receptor with important biological activity.

References: Thompson AJ, et al. VUF10166, a novel compound with differing activities at 5-HT₃A and 5-HT₃AB receptors. J Pharmacol Exp Ther. 2012 May;341(2):350-9.

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Molecular Weight (MW)262.74
Molecular FormulaC13H15ClN4
CAS No.155584-74-0
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
Solubility In VitroDMSO: 21 mg/mL (79.9 mM)r
Water: <1 mg/mLr
Ethanol: 61 mg/mL (232.2 mM)
SynonymsVUF 10166; VUF-10166; VUF10166;
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM3.8060 mL19.0302 mL38.0604 mL76.1209 mL
5mM0.7612 mL3.8060 mL7.6121 mL15.2242 mL
10mM0.3806 mL1.9030 mL3.8060 mL7.6121 mL
20mM0.1903 mL0.9515 mL1.9030 mL3.8060 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.