Eucalyptol

This product is for research use only, not for human use. We do not sell to patients.

Eucalyptol
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
500mg$225Check With Us
1g$335Check With Us
5g$910Check With Us

Cat #: V20852 CAS #: 470-82-6 Purity ≥ 99%

Description: Eucalyptol (1,8-epoxy-p-Menthane; Cineole; 1,8-Cineole; NSC-617) is an organic compound and a colorless liquid, acting an inhibitor of 5-HT3 receptor ,potassium channel, TNF-α and IL-1β.

References: Khan A, et al. 1,8-cineole (eucalyptol) mitigates inflammation in amyloid Beta toxicated PC12 cells: relevance to Alzheimer's disease. Neurochem Res. 2014 Feb;39(2):344-52.[3]

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Product Promise

Promise
Molecular Weight (MW)154.25
Molecular FormulaC10H18O
CAS No.470-82-6
ProtocolIn VitroEucalyptol (Cin) treatment significantly decreases the ROS level in Aβ25-35 treated cells in a dose dependent manner. Eucalyptol treatment significantly decreases the NO level in Aβ25-35 treated cells in a dose dependent manner (p<0.05 and p<0.01). Eucalyptol treatment also significantly decreases IL-1βlevel in Aβ25-35 treated cells in a dose dependent manner (p<0.05 and p<0.01) as compare to Aβ25-35 treated PC12 cells. IL-6 level is also attenuated by Eucalyptol in dose dependent manner (p<0.05 and p<0.01) as compare to Aβ25-35 treated cells
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM6.4830 mL32.4149 mL64.8298 mL129.6596 mL
5mM1.2966 mL6.4830 mL12.9660 mL25.9319 mL
10mM0.6483 mL3.2415 mL6.4830 mL12.9660 mL
20mM0.3241 mL1.6207 mL3.2415 mL6.4830 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
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Concentration
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Volume
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Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
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Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.