WAY-100635 Maleate
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 250mg | $859 | Check With Us |
| 500mg | $1180 | Check With Us |
| 1g | $1770 | Check With Us |
: Cat #: V0996 CAS #: 1092679-51-0 or 634908-75-1 Purity ≥ 98%
Description: WAY-100635 maleate (WAY 100635; WAY100635), the maleate salt of WAY-100635, is a novel, potent and selective antagonist of serotonin 5-HT1A receptor with important biological activity.
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- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 538.64 |
|---|---|
| Molecular Formula | C25H34N4O2.C4H4O4 |
| CAS No. | 1092679-51-0 or 634908-75-1 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: 85 mg/mL (157.8 mM)r |
| Water: <1 mg/mLr | |
| Ethanol: 85 mg/mL (157.8 mM) | |
| Synonyms | WAY 100635 Maleate; WAY-100635; WAY100635 |
| Protocol | In Vivo | WAY-100635 (1 mg/kg; subcutaneous injection; male Sprague-Dawley rats) treatment abolishes the reduction of the severity of abstinence signs induced by Rhodiola rosea administration in nicotine-dependent rat |
|---|---|---|
| Animal model | Male Sprague-Dawley rats (220-240 g) | |
| Dosages | 1 mg/kg | |
| Administration | Subcutaneous injection (Pharmacokinetic study) |
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 1.8565 mL | 9.2826 mL | 18.5653 mL | 37.1306 mL |
| 5mM | 0.3713 mL | 1.8565 mL | 3.7131 mL | 7.4261 mL |
| 10mM | 0.1857 mL | 0.9283 mL | 1.8565 mL | 3.7131 mL |
| 20mM | 0.0928 mL | 0.4641 mL | 0.9283 mL | 1.8565 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.