Fluoxetine HCl (LY-110140)
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 5g | $299 | Check With Us |
| 10g | $480 | Check With Us |
| 20g | $720 | Check With Us |
: Cat #: V0965 CAS #: 56296-78-7 Purity ≥ 98%
Description: Fluoxetine HCl (LY-110140; Lilly-110140; Prozac, Sarafem, Animex-On, Pulvules, Eufor, Portal), the HCl salt of fluoxetine, is a potent and selective serotonin-reuptake inhibitor (SSRI) at the neuronal membrane with anti-depressant activity.
Top Publications Citing Invivochem Products
Publications Citing InvivoChem Products
Product Promise
- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 345.79 |
|---|---|
| Molecular Formula | C17H18F3NO.HCl |
| CAS No. | 56296-78-7 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: 69 mg/mL (199.5 mM)r |
| Water: <1 mg/mLr | |
| Ethanol: 69 mg/mL (199.5 mM) | |
| SMILES Code | FC(C1=CC=C(OC(C2=CC=CC=C2)CCNC)C=C1)(F)F.[H]Cl |
| Synonyms | Lilly110140; Lilly-110140; LY-110140; Lilly 110140; Fluoxetine, Prozac, Sarafem, Fluoxetine, Animex-On, Fluoxetin, Pulvules, Eufor, Portal; LY110140; LY 110140 |
| Protocol | In Vitro | Fluoxetine hydrochloride (LY 110140) blocks the downregulation of cell proliferation resulting from inescapable shock (IS) of hippocampal cell |
|---|---|---|
| In Vivo | Fluoxetine hydrochloride (LY 110140) treatment also reverses the deficit in escape latency observed in animals exposed to inescapable shock in adult male Sprague-Dawley rats |
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.8919 mL | 14.4596 mL | 28.9193 mL | 57.8386 mL |
| 5mM | 0.5784 mL | 2.8919 mL | 5.7839 mL | 11.5677 mL |
| 10mM | 0.2892 mL | 1.4460 mL | 2.8919 mL | 5.7839 mL |
| 20mM | 0.1446 mL | 0.7230 mL | 1.4460 mL | 2.8919 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.