Rifampin (Rifampicin)

This product is for research use only, not for human use. We do not sell to patients.

For small sizes, please check our retail website as below: www.invivochem.com

Size	Price	Stock
10g	$300	Check With Us
50g	$550	Check With Us
100g	$825	Check With Us

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Cat #: V1468 CAS #: 13292-46-1 Purity ≥ 98%

Description: Rifampin (Rimactane; Arficin; Arzide; Rifampicin; Rifadin; Rimactane; Rimactan; Tubocin; Archidyn; Benemicin; Doloresum; Eremfat; Fenampicin; Sinerdol), an approved broad spectrum and semisynthetic antibiotic found in Streptomyces mediterranei, is mainly used to treat various bacterial infections such as TB-tuberculosis, leprosy, mycobacterium avium complex, and Legionnaires' disease.

References: Erokhina MV, et al. [In vitro development of rifampicin resistance in the epithelial cells]. Probl Tuberk Bolezn Legk. 2006;(8):58-61.

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Physicochemical and Storage Information
Protocol
Related Biological Data
Stock Solution Preparation
Quality Control Documentation

Molecular Weight (MW)	822.94
Molecular Formula	C43H58N4O12
CAS No.	13292-46-1
Storage	-20℃ for 3 years in powder formr
Storage	-80℃ for 2 years in solvent
Solubility In Vitro	DMSO: 100 mg/mL (121.5 mM)r
	Water: <1 mg/mLr
	Ethanol: <1 mg/mL
Synonyms	Rimactane; Arficin; Arzide; Rifampicin; Rifadin; Rifampin; Rimactane; Rimactan; Tubocin; Archidyn; Benemicin; Doloresum; Eremfat; Fenampicin; Sinerdol;

Protocol	In Vitro	Rifampicin (100 mg/mL) can block the functional activity of P-glycoprotein. Rifampicin is not a substract for P-glycoprotein. The mechanism of rifampicin resistance is unassociated with the functional activity of P-glycoprotein

These protocols are for reference only. InvivoChem does not independently validate these methods.

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	1.2152 mL	6.0758 mL	12.1516 mL	24.3031 mL
5mM	0.2430 mL	1.2152 mL	2.4303 mL	4.8606 mL
10mM	0.1215 mL	0.6076 mL	1.2152 mL	2.4303 mL
20mM	0.0608 mL	0.3038 mL	0.6076 mL	1.2152 mL

Quality Control Documentation	Select Batch Purity ≥ 98% COA MSDS NMR HPLC

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.