Trifluridine (trifluorothymidine)

This product is for research use only, not for human use. We do not sell to patients.

For small sizes, please check our retail website as below: www.invivochem.com

Size	Price	Stock
1g	$390	Check With Us
2g	$650	Check With Us
5g	$980	Check With Us

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Cat #: V1461 CAS #: 70-00-8 Purity ≥ 98%

Description: Trifluridine (also known as trifluorothymidine; FTD; NSC-529182; NSC-75520; NSC529182; NSC75520; Viroptic), an inhibitor of the thymidylate synthase and DNA synthesis, is an approved anti-herpesvirus antiviral agent/medications used mainly for treating infections in the eye.

References: Suzuki N, et al. Mode of action of trifluorothymidine (TFT) against DNA replication and repair enzymes. Int J Oncol. 2011 Jul;39(1):263-70.

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Physicochemical and Storage Information
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Related Biological Data
Stock Solution Preparation
Quality Control Documentation

Molecular Weight (MW)	296.2
Molecular Formula	C10H11F3N2O5
CAS No.	70-00-8
Storage	-20℃ for 3 years in powder formr
Storage	-80℃ for 2 years in solvent
Solubility In Vitro	DMSO: 59 mg/mL (199.2 mM)r
	Water: 59 mg/mL (199.2 mM)r
	Ethanol: 59 mg/mL (199.2 mM)
Synonyms	FTD; NSC 529182; NSC 75520; NSC-529182; NSC-75520; NSC529182; NSC75520; Viroptic; 2-Deoxy-5-trifluoromethyluridine; Trifluridine; 5-Trifluorothymidine

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	3.3761 mL	16.8805 mL	33.7610 mL	67.5219 mL
5mM	0.6752 mL	3.3761 mL	6.7522 mL	13.5044 mL
10mM	0.3376 mL	1.6880 mL	3.3761 mL	6.7522 mL
20mM	0.1688 mL	0.8440 mL	1.6880 mL	3.3761 mL

Quality Control Documentation	Select Batch Purity ≥ 98% COA MSDS NMR HPLC

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.