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Cutamesine (SA 4503; AGY 94806)

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Cutamesine (SA 4503; AGY 94806)
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
250mg$1340Check With Us
500mg$1950Check With Us
1g$2930Check With Us

Cat #: V0097 CAS #: 165377-43-5 Purity ≥ 99%

Description: Cutamesine (SA-4503; AGY-94806) is a selective and potent sigma-1 (σ1) receptor agonist with an IC50 of 17.4 nM in guinea pig brain membranes, 100-fold less selective for the sigma 2 receptor.

References: Matsuno K, et al. Binding properties of SA4503, a novel and selective sigma 1 receptor agonist. Eur J Pharmacol. 1996 Jun 13;306(1-3):271-9.

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Molecular Weight (MW)368.51
Molecular FormulaC₂₃H₃₂N₂O₂
CAS No.165377-43-5
Storage-20℃ for 3 years in powder formrrrr
-80℃ for 2 years in solvent
Solubility In VitroDMSO: 10 mg/mLrrrr
Water: < 1 mg/mLrrrr
Ethanol: < 1 mg/mL
SMILES CodeCOC1=CC=C(CCN2CCN(CCCC3=CC=CC=C3)CC2)C=C1OC
SynonymsSA4503; SA-4503; SA 4503; AGY94806; AGY 94806; AGY-94806; Cutamesine
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.7136 mL13.5682 mL27.1363 mL54.2726 mL
5mM0.5427 mL2.7136 mL5.4273 mL10.8545 mL
10mM0.2714 mL1.3568 mL2.7136 mL5.4273 mL
20mM0.1357 mL0.6784 mL1.3568 mL2.7136 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
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Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.