Pralidoxime Chloride (2-PAM chloride)
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 2g | $400 | To Be Confirmed |
| 5g | $700 | To Be Confirmed |
| 10g | $1050 | To Be Confirmed |
: Cat #: V25970 CAS #: 51-15-0 Purity ≥ 99%
Description: Pralidoxime Chloride (2-PAM chloride) is a useful anti-dote agent for organophosphate poisoning.
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- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 172.61 |
|---|---|
| Molecular Formula | C7H9ClN2O |
| CAS No. | 51-15-0 |
| SMILES Code | CN1C=CC=CC1=C[NH+]=O.[Cl-]. |
| Protocol | In Vivo | Pralidoxime chloride (10-150 mg/kg; intramuscular administration, once) reverses paraoxon-induced respiratory toxicity in mice |
|---|---|---|
| Animal model | F1B6D2 mice (male, administered subcutaneously diethylparaoxon) | |
| Dosages | 10, 50, 100, and 150 mg/kg | |
| Administration | Intramuscular administration, once |
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 5.7934 mL | 28.9670 mL | 57.9341 mL | 115.8681 mL |
| 5mM | 1.1587 mL | 5.7934 mL | 11.5868 mL | 23.1736 mL |
| 10mM | 0.5793 mL | 2.8967 mL | 5.7934 mL | 11.5868 mL |
| 20mM | 0.2897 mL | 1.4484 mL | 2.8967 mL | 5.7934 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.