Cinchonidine
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 10g | $250 | Check With Us |
| 50g | $700 | Check With Us |
| 100g | $1050 | Check With Us |
: Cat #: V2001 CAS #: 485-71-2 Purity ≥ 98%
Description: Cinchonidine is a natural cinchona alkaloid with antimalarial activity.
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- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 294.39 |
|---|---|
| Molecular Formula | C19H22N2O |
| CAS No. | 485-71-2 |
| Storage | -20℃ for 3 years in powder formrr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: 59 mg/mL (200.41 mM)rr |
| Water: <1 mg/mLrr | |
| Ethanol: 59 mg/mL (200.41 mM) | |
| SMILES Code | C=C[C@@H](C[N@@]1CC2 [C@@H]2C[C@H]1[C@H](O)C3=CC=NC4=CC=CC=C |
| Synonyms | α-Quinidine; Cinchonidine dihydrochloride, Cinchonidine sulfate, Cinchovatine, alpha-Quinidine |
| Protocol | In Vitro | Cinchonidine (α-Quinidine) is a cinchona alkaloid found in Cinchona officinalis and Gongronema latifolium. A building block used in asymmetric synthesis in organic chemistry. Weak inhibitor of serotonin transporter (SERT) with Kis of 330, 4.2, 36, 196, 15 μM for dSERT, hSERT, hSERT I172M, hSERT S438T, hSERT Y95F, respectively |
|---|
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 3.3969 mL | 16.9843 mL | 33.9685 mL | 67.9371 mL |
| 5mM | 0.6794 mL | 3.3969 mL | 6.7937 mL | 13.5874 mL |
| 10mM | 0.3397 mL | 1.6984 mL | 3.3969 mL | 6.7937 mL |
| 20mM | 0.1698 mL | 0.8492 mL | 1.6984 mL | 3.3969 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.