Deferoxamine mesylate
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 5g | $450 | To Be Confirmed |
| 10g | $750 | To Be Confirmed |
| 20g | $1125 | To Be Confirmed |
: Cat #: V15809 CAS #: 138-14-7 Purity ≥ 98%
Description: Deferoxamine is an novel iron chelator that is able to bind to free iron in a stable complex, it is also a bacterial siderophore produced by the Actinobacteria Streptomyces pilosus.
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- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 656.79 |
|---|---|
| Molecular Formula | C26H52N6O11S |
| CAS No. | 138-14-7 |
| Protocol | In Vitro | Deferoxamine mesylate (1 mM; 16 h or 4 weeks) improves HIF-1α function under hypoxic and hyperglycemic conditions and decreases ROS in MEFs cells |
|---|---|---|
| In Vivo | Deferoxamine mesylate (560.68 mg/per; drip-on; once daily for 21 days) enhances wound healing and increases neovascularization in aged or diabetic mice | |
| Animal model | Aged (21-month-old) and diabetic (12-week-old) C57BL/6J mice (excisional wound model) | |
| Dosages | Aged (21-month-old) and diabetic (12-week-old) C57BL/6J mice (excisional wound model) | |
| Administration | Aged (21-month-old) and diabetic (12-week-old) C57BL/6J mice (excisional wound model) |
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 1.5226 mL | 7.6128 mL | 15.2256 mL | 30.4511 mL |
| 5mM | 0.3045 mL | 1.5226 mL | 3.0451 mL | 6.0902 mL |
| 10mM | 0.1523 mL | 0.7613 mL | 1.5226 mL | 3.0451 mL |
| 20mM | 0.0761 mL | 0.3806 mL | 0.7613 mL | 1.5226 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.