EUK 134
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 500mg | $400 | Check With Us |
| 1g | $600 | Check With Us |
| 5g | $1800 | Check With Us |
: Cat #: V1315 CAS #: 81065-76-1 Purity ≥ 98%
Description: EUK 134 (EUK-134; EUK134), a synthetic and cell permeable superoxide dismutase (SOD)/catalase mimetic, is a novel antioxidant compound that exhibits potent antioxidant activities.
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- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 416.74 |
|---|---|
| Molecular Formula | C18H18ClMnN2O4 |
| CAS No. | 81065-76-1 |
| Storage | -20℃ for 3 years in powder formrr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: 83 mg/mL (199.2 mM)rr |
| Water: 13 mg/mL (31.2 mM)rr | |
| Ethanol: <1 mg/mL | |
| SMILES Code | COC1=C2C(C[N]3CC[N]4=CC5=CC=CC(OC)=C5O[Mn+3]34([O-2]2)[Cl-])=CC=C1 |
| Synonyms | EUK-134; EUK-134; EUK-134 |
| Protocol | In Vitro | EUK-134 (10-300 μM) is able to improve cell viability and reduces Paraquat (1 mM)-induced cell death significantly via dismutation or scavenging of superoxide anions and reduces hydroxyl radical generation |
|---|
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.3996 mL | 11.9979 mL | 23.9958 mL | 47.9916 mL |
| 5mM | 0.4799 mL | 2.3996 mL | 4.7992 mL | 9.5983 mL |
| 10mM | 0.2400 mL | 1.1998 mL | 2.3996 mL | 4.7992 mL |
| 20mM | 0.1200 mL | 0.5999 mL | 1.1998 mL | 2.3996 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.