Licochalcone B

This product is for research use only, not for human use. We do not sell to patients.

Licochalcone B
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
50mg$650Check With Us
100mg$990Check With Us
200mg$1485Check With Us

Cat #: V24107 CAS #: 58749-23-8 Purity ≥ 99%

Description: Licochalcone B, a naturally occuring chalcone compound isolated from the root of Glycyrrhiza inflate, is an inhibitor of phosphorylation of NF-kappaB p65 in LPS signaling pathway.

References: Cao Y, et al. Licochalcone B, a chalcone derivative from Glycyrrhiza inflata, as a multifunctional agent for the treatment of Alzheimer's disease. Nat Prod Res. 2018 Oct 22:1-4.

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Product Promise

Promise
Molecular Weight (MW)286.28
Molecular FormulaC16H14O5
CAS No.58749-23-8
SMILES CodeOC1=CC=C(/C=C/C(C2=CC=C(O)C(O)=C2OC)=O)C=C1
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM3.4931 mL17.4654 mL34.9308 mL69.8617 mL
5mM0.6986 mL3.4931 mL6.9862 mL13.9723 mL
10mM0.3493 mL1.7465 mL3.4931 mL6.9862 mL
20mM0.1747 mL0.8733 mL1.7465 mL3.4931 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.