CRANAD-2

This product is for research use only, not for human use. We do not sell to patients.

CRANAD-2
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
250mg$1000To Be Confirmed
500mg$1750To Be Confirmed
1g$2625To Be Confirmed

Cat #: V18783 CAS #: 1193447-34-5 Purity ≥ 99%

Description: CRANAD-2 is a difluoroboron-based curcumin acting as a near-infrared (NIR) Aβ plaque-specific fluorescent probe for in vivo detection of amyloid-beta deposits.

References: an C, et al. Design, synthesis, and testing of difluoroboron-derivatized curcumins as near-infrared probes for in vivo detection of amyloid-beta deposits. J Am Chem Soc. 2009 Oct 28;131(42):15257-61. 

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Molecular Weight (MW)410.26
Molecular FormulaC23H25BF2N2O2
CAS No.1193447-34-5
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.4375 mL12.1874 mL24.3748 mL48.7496 mL
5mM0.4875 mL2.4375 mL4.8750 mL9.7499 mL
10mM0.2437 mL1.2187 mL2.4375 mL4.8750 mL
20mM0.1219 mL0.6094 mL1.2187 mL2.4375 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.