Lotilaner
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 50mg | $1400 | To Be Confirmed |
| 100mg | $2100 | To Be Confirmed |
| 200mg | $3150 | To Be Confirmed |
: Cat #: V24414 CAS #: 1369852-71-0 Purity ≥ 99%
Description: Lotilaner (Credelio) is a potent insecticide agent (veterinary drug) acting as a non-competitive antagonist of insect GABA receptors.
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- Related Biological Data
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| Molecular Weight (MW) | 596.7504 |
|---|---|
| Molecular Formula | C20H14Cl3F6N3O3S |
| CAS No. | 1369852-71-0 |
| Protocol | In Vitro | Lotilaner shows IC50s of 38.25 ± 3.75, 52.40 ± 4.54, 36.79 ± 4.39 nM for Drosophila melanogaster dieldrin/fipronil-resistant forms (DmR2), Lepeophtheirus salmonis (Ls) and Rhipicephalus microplus (Rm) GABACl receptors, respectively |
|---|
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 1.6757 mL | 8.3787 mL | 16.7574 mL | 33.5148 mL |
| 5mM | 0.3351 mL | 1.6757 mL | 3.3515 mL | 6.7030 mL |
| 10mM | 0.1676 mL | 0.8379 mL | 1.6757 mL | 3.3515 mL |
| 20mM | 0.0838 mL | 0.4189 mL | 0.8379 mL | 1.6757 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.