6-OHDA HBr (Oxidopamine hydrobromide)
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 1g | $300 | Check With Us |
| 5g | $600 | Check With Us |
| 10g | $900 | Check With Us |
: Cat #: V7444 CAS #: 636-00-0 Purity ≥ 98%
Description: Oxidopamine hydrobromide (6-OHDA hydrobromide; 6-OHDA HBr) is a neurotoxin acting as a dopamine antagonist and destroying catecholaminergic terminals.
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- Related Biological Data
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| Molecular Weight (MW) | 250.09 |
|---|---|
| Molecular Formula | C8H12BrNO3 |
| CAS No. | 636-00-0 |
| Synonyms | 6-Hydroxydopamine hydrobromide; 6-OHDA hydrobromide; 6-OHDA HBr; 6 OHDA HBr; 6OHDA HBr; 6-OHDA Hydrobromide; 6 OHDA Hydrobromide; 6OHDA Hydrobromide; 6-Hydroxydopamine Hydrobromide; 6Hydroxydopamine Hydrobromide; 6 Hydroxydopamine Hydrobromide; 6-Hydroxydopamine HBr; 6 Hydroxydopamine HBr; |
| Protocol | In Vivo | Oxidopamine hydrobromide (5 μg/2 μL, unilaterally injected into the right striatum) induced dopaminergic neuronal degeneration in the substantia nigra in rats |
|---|
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 3.9986 mL | 19.9928 mL | 39.9856 mL | 79.9712 mL |
| 5mM | 0.7997 mL | 3.9986 mL | 7.9971 mL | 15.9942 mL |
| 10mM | 0.3999 mL | 1.9993 mL | 3.9986 mL | 7.9971 mL |
| 20mM | 0.1999 mL | 0.9996 mL | 1.9993 mL | 3.9986 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
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Concentration
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Volume
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Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
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Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
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Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.