Sultopride Hydrochloride

This product is for research use only, not for human use. We do not sell to patients.

Sultopride Hydrochloride
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
50mg$550To Be Confirmed
100mg$825To Be Confirmed
200mg$1240To Be Confirmed

Cat #: V5703 CAS #: 23694-17-9 Purity ≥ 98%

Description: Sultopride Hydrochloride is a selective D2 and D3 receptor antagonist.

References: Moriuchi K, et al. Differences in effects of sultopride and sulpiride on dopamine turnover in rat brain. Neurochem Res. 1995 Jan;20(1):95-9.

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Molecular Weight (MW)390.92
Molecular FormulaC17H27ClN2O4S
CAS No.23694-17-9
SMILES CodeO=C(NCC1N(CC)CCC1)C2=CC(S(=O)(CC)=O)=CC=C2OC.[H]Cl;
SynonymsSultopride Hydrochloride; Sultopride HCl;
ProtocolIn VivoSultopride hydrochloride (LIN-1418 hydrochloride) is a selective antagonist of dopamine D2 receptor. DOPAC and HVA levels in the striatum, the nucleus accumbens and the medial prefrontal cortex are higher in the rats treated with Sultopride hydrochloride and sulpiride than those of the controls. In the striatum, DOPAC and HVA levels are higher in the Sultopride hydrochloride-treated rats than the sulpiride-treated rats (p<0.05). In the nucleus accumbens, DOPAC levels are higher in the Sultopride hydrochloride-treated rats than sulpiride treated rats (p<0.05). In the Sultopride hydrochloride-treated rats, DOPAC and HVA levels are higher in the striatum or in the nucleus accumbens than in the medial prefrontal cortex (p<0.05)
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.5581 mL12.7903 mL25.5807 mL51.1614 mL
5mM0.5116 mL2.5581 mL5.1161 mL10.2323 mL
10mM0.2558 mL1.2790 mL2.5581 mL5.1161 mL
20mM0.1279 mL0.6395 mL1.2790 mL2.5581 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.