Etilevodopa

This product is for research use only, not for human use. We do not sell to patients.

Etilevodopa
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
25mg$1450To Be Confirmed
50mg$2175To Be Confirmed
100mg$3263To Be Confirmed

Cat #: V20819 CAS #: 37178-37-3 Purity ≥ 99%

Description: Etilevodopa (TV-1203; Levodopa ethyl ester; L-Dopa ethyl ester; O-Ethyl-DOPA) is a dopaminergic agent used for the treatment for Parkinson's disease.

References: Djaldetti R, et al. Pharmacokinetics of etilevodopa compared to levodopa in patients with Parkinson's disease: an open-label, randomized, crossover study. Clin Neuropharmacol. 2003 Nov-Dec;26(6):322-6.

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Molecular Weight (MW)225.24
Molecular FormulaC11H15NO4
CAS No.37178-37-3
ProtocolIn VitroEtilevodopa (L-Dopa ethyl ester) passes unchanged through the stomach to the duodenum, where it is rapidly hydrolyzed by local esterases to Levodopa and ethanol, and is subsequently absorbed into the blood stream as Levodopa
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM4.4397 mL22.1985 mL44.3971 mL88.7942 mL
5mM0.8879 mL4.4397 mL8.8794 mL17.7588 mL
10mM0.4440 mL2.2199 mL4.4397 mL8.8794 mL
20mM0.2220 mL1.1099 mL2.2199 mL4.4397 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
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Concentration
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Volume
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Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.