Metoprolol
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 25g | $450 | Check With Us |
| 50g | $750 | Check With Us |
| 100g | $1125 | Check With Us |
: Cat #: V13734 CAS #: 51384-51-1 Purity ≥ 99%
Description: Metoprolol (Lanoc; Selopral; Ritmolol; Lopressor; Metomerck; Metop; Toprol) is a potent β1 adrenergic receptor blocker and an approved drug for the treatment of high blood pressure and chest pain.
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- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 267.36 |
|---|---|
| Molecular Formula | C15H25NO3 |
| CAS No. | 51384-51-1 |
| Protocol | In Vitro | Metoprolol (0-1000 μg/mL; 24-72 h) shows cytotoxic effect on U937 and MOLT-4 cells dose and time dependently |
|---|---|---|
| In Vivo | Metoprolol (2.5 mg/kg/h; infusion; 11 weeks) reduces proinflammatory cytokines and atherosclerosis in ApoE−/− Mice | |
| Animal model | Male ApoE−/− mice | |
| Dosages | 2.5 mg/kg/h | |
| Administration | Via osmotic minipumps, 11 weeks |
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 3.7403 mL | 18.7014 mL | 37.4028 mL | 74.8055 mL |
| 5mM | 0.7481 mL | 3.7403 mL | 7.4806 mL | 14.9611 mL |
| 10mM | 0.3740 mL | 1.8701 mL | 3.7403 mL | 7.4806 mL |
| 20mM | 0.1870 mL | 0.9351 mL | 1.8701 mL | 3.7403 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.