Oxaprozin (Oxaprozinum; Wy21743)
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 25g | $650 | Check With Us |
| 50g | $980 | Check With Us |
| 100g | $1470 | Check With Us |
: Cat #: V1065 CAS #: 21256-18-8 Purity ≥ 98%
Description: Oxaprozin (Oxaprozinum, DL-8280, WY-21743; DR-3355, Hoe-280, ORF-28489, Ru-43280, Tarivid) is a potent nonsteroidal anti-inflammatory drug (NSAID) with analgesic and antipyretic properties.
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- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 293.32 |
|---|---|
| Molecular Formula | C18H15NO3 |
| CAS No. | 21256-18-8 |
| Storage | -20℃ for 3 years in powder formrr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: 59 mg/mL (201.1 mM)rr |
| Water: <1 mg/mLrr | |
| Ethanol: 27 mg/mL (92.0 mM) | |
| SMILES Code | CC1COC2=C3N1C=C(C(O)=O)C(C3=CC(F)=C2N4CCN(C)CC4)=O |
| Synonyms | WY21743; Oxaprozin, Oxaprozinum, DL-8280, WY-21743; WY 21743; DR-3355, Hoe-280, ORF-28489, Ru-43280, Tarivid |
| Protocol | In Vitro | Oxaprozin induces apoptosis in a dose-dependent manner. Oxaprozin increases caspase-3 activity in the activated but not in the resting condition. NF-κB activation is inhibited by Oxaprozin (50 μM). Oxaprozin inhibits activation of the IKK system induced by the reagent IκBα |
|---|
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 3.4092 mL | 17.0462 mL | 34.0925 mL | 68.1849 mL |
| 5mM | 0.6818 mL | 3.4092 mL | 6.8185 mL | 13.6370 mL |
| 10mM | 0.3409 mL | 1.7046 mL | 3.4092 mL | 6.8185 mL |
| 20mM | 0.1705 mL | 0.8523 mL | 1.7046 mL | 3.4092 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
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Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
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Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.