Niflumic acid
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 25g | $450 | Check With Us |
| 50g | $600 | Check With Us |
| 100g | $900 | Check With Us |
: Cat #: V1064 CAS #: 4394-00-7 Purity ≥ 98%
Description: Niflumic acid (Flunir, Donalgin, Niflactol, Niflugel, Nifluril) is a potent inhibitor of cyclooxygenase-2 (COX-2) enzyme with potential anti-inflammatory and analgesic activity.
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| Molecular Weight (MW) | 282.22 |
|---|---|
| Molecular Formula | C13H9F3N2O2 |
| CAS No. | 4394-00-7 |
| Storage | -20℃ for 3 years in powder formrrr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: 56 mg/mL (198.4 mM)rrr |
| Water:<1 mg/mLrrr | |
| Ethanol: <1 mg/mL | |
| SMILES Code | O=C(C1=CC=CN=C1NC2=CC=CC(C(F)(F)F)=C2)O |
| Synonyms | Flunir, Niflactol, Niflugel, Niflumic Acid, Donalgin, Nifluril |
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 3.5433 mL | 17.7167 mL | 35.4333 mL | 70.8667 mL |
| 5mM | 0.7087 mL | 3.5433 mL | 7.0867 mL | 14.1733 mL |
| 10mM | 0.3543 mL | 1.7717 mL | 3.5433 mL | 7.0867 mL |
| 20mM | 0.1772 mL | 0.8858 mL | 1.7717 mL | 3.5433 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.