Ketorolac (RS37619)
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 5g | $500 | Check With Us |
| 10g | $850 | Check With Us |
| 20g | $1280 | Check With Us |
: Cat #: V1050 CAS #: 74103-06-3 Purity ≥ 98%
Description: Ketorolac (Toradol, Acular, RS 37619; RS37619; Sprix, Macril, Acuvail, Lixidol), an NSAID (non-steroidal anti-inflammatory drug), is a potent and non-selective COX inhibitor of COX-1 and COX-2 with potential anti-inflammatory activity.
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- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 255.27 |
|---|---|
| Molecular Formula | C15H13N1O3 |
| CAS No. | 74103-06-3 |
| Storage | -20℃ for 3 years in powder formrrr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: 10 mMrrr |
| Water: <1 mg/mLrrr | |
| Ethanol: N/A | |
| SMILES Code | O=C(C1C2=CC=C(C(C3=CC=CC=C3)=O)N2CC1)O |
| Synonyms | RS-37619; Ketorolac, Toradol, Acular, RS 37619; RS37619; Sprix, Macril, Acuvail, Lixidol |
| Protocol | In Vitro | Ketorolac salt (0-5 μM; 48 h) inhibits the expression of DDX3 protein, and induces apoptosis in H357 cells |
|---|---|---|
| In Vivo | Ketorolac salt (20 and 30 mg/kg; i.p.; two times in a week for 3 weeks) reduces oral carcinogenesis in mice |
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 3.9174 mL | 19.5871 mL | 39.1742 mL | 78.3484 mL |
| 5mM | 0.7835 mL | 3.9174 mL | 7.8348 mL | 15.6697 mL |
| 10mM | 0.3917 mL | 1.9587 mL | 3.9174 mL | 7.8348 mL |
| 20mM | 0.1959 mL | 0.9794 mL | 1.9587 mL | 3.9174 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.