Phenacetin (Acetophenetidin)
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 100g | $300 | Check With Us |
| 200g | $350 | Check With Us |
| 500g | $550 | Check With Us |
: Cat #: V1058 CAS #: 62-44-2 Purity ≥ 98%
Description: Phenacetin (also known as acetophenetidin) is a potent non-opioid analgesic agent without anti-inflammatory properties.
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- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 179.22 |
|---|---|
| Molecular Formula | C10H13NO2 |
| CAS No. | 62-44-2 |
| Storage | -20℃ for 3 years in powder formrr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: 36 mg/mL (200.9 mM)rr |
| Water: <1 mg/mLrr | |
| Ethanol: 36 mg/mL (200.9 mM) | |
| SMILES Code | CC(NC1=CC=C(OCC)C=C1)=O |
| Synonyms | Acetophenetidin |
| Protocol | In Vitro | Phenacetin is a substrate widely used as an in vitro and in vivo probe to measure the activity of CYP1A2, because the metabolism of phenacetin to acetaminophen is thought to be a selective CYP1A2-mediated reaction |
|---|---|---|
| In Vivo | Phenacetin exhibits elimination half-life (rat 2.06 h) and Cmax (6,728.3 μg/L) following oral administration (rat 20 mg/kg) |
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 5.5797 mL | 27.8987 mL | 55.7973 mL | 111.5947 mL |
| 5mM | 1.1159 mL | 5.5797 mL | 11.1595 mL | 22.3189 mL |
| 10mM | 0.5580 mL | 2.7899 mL | 5.5797 mL | 11.1595 mL |
| 20mM | 0.2790 mL | 1.3949 mL | 2.7899 mL | 5.5797 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.