Carubicin | CAS 50935-04-1

Carubicin

This product is for research use only, not for human use. We do not sell to patients.

For small sizes, please check our retail website as below: www.invivochem.com

Size	Price	Stock
100mg	$920	To Be Confirmed
250mg	$1600	To Be Confirmed
500mg	$2400	To Be Confirmed

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Cat #: V4898 CAS #: 50935-04-1 Purity ≥ 98%

Description: Carubicin (Karminomitsin; Carminomicin I; karminomycin; Demethyldaunomycin), a potent anticancer agent and DNA intercalator, is a natural anthracycline antineoplastic antibiotic isolated from the bacterium Actinomadura carminata.

References: Woldemichael GM, et al. Carminomycin I is an apoptosis inducer that targets the Golgi complex in clear cell renal carcinoma cells. Cancer Res. 2011 Jan 1;71(1):134-42.

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Physicochemical and Storage Information
Protocol
Related Biological Data
Stock Solution Preparation
Quality Control Documentation

Molecular Weight (MW)	513.49
Molecular Formula	C26H27NO10
CAS No.	50935-04-1
Storage	-20℃ for 3 years in powder formr
Storage	-80℃ for 2 years in solvent
SMILES Code	O=C1C2=C(O)C([C@@H](O[C@@H]3O[C@@H](C)[C@@H](O)[C@@H](N)C3)C[C@](O)(C(C)=O)C4)=C4C(O)=C2C(C5=C1C(O)=CC=C5)=O
Synonyms	carminomycin; Demethyldaunomycin; Karminomitsin; karminomycin; CM; Antibiotic R 588A; Carminomicin I; Carminomycin I; Carubicin;

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	1.9475 mL	9.7373 mL	19.4746 mL	38.9492 mL
5mM	0.3895 mL	1.9475 mL	3.8949 mL	7.7898 mL
10mM	0.1947 mL	0.9737 mL	1.9475 mL	3.8949 mL
20mM	0.0974 mL	0.4869 mL	0.9737 mL	1.9475 mL

Quality Control Documentation	Select Batch Purity ≥ 98% COA MSDS NMR HPLC

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.