Medicarpin
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
Size | Price | Stock |
---|---|---|
100mg | $1875 | Check With Us |
200mg | $2810 | Check With Us |
500mg | $4745 | Check With Us |
Cat #: V19104 CAS #: 32383-76-9 Purity ≥ 98%
Description: Medicarpin is a naturally occuring flavonoid extracted from the herb of Hedysarum polybotrys Hand. -Mazz.
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Molecular Weight (MW) | 270.28 |
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Molecular Formula | C16H14O4 |
CAS No. | 32383-76-9 |
SMILES Code | OC1=CC=C2[C@](OC3=CC(OC)=CC=C34)([H])[C@]4([H])COC2=C1 |
Synonyms | NSC 350085; NSC-350085; NSC350085; Medicarpin; Demethylhomopterocarpin; Medicarpin, (-)-; |
Protocol | In Vitro | Medicarpin (90 µM; for 48 h) triggers apoptosis in sensitive as well as multidrug resistant P388 cells. P-glycoprotein-expressing P388/DOX cells does not show resistance to medicarpin (IC50≈90 µM for P388 and P388/DOX cells). |
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These protocols are for reference only. InvivoChem does not
independently validate these methods.
Solvent volume to be added | Mass (the weight of a compound) | |||
---|---|---|---|---|
Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
1mM | 3.6999 mL | 18.4993 mL | 36.9987 mL | 73.9973 mL |
5mM | 0.7400 mL | 3.6999 mL | 7.3997 mL | 14.7995 mL |
10mM | 0.3700 mL | 1.8499 mL | 3.6999 mL | 7.3997 mL |
20mM | 0.1850 mL | 0.9250 mL | 1.8499 mL | 3.6999 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.