HS-1793
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 250mg | $1150 | Check With Us |
| 500mg | $1700 | Check With Us |
| 1g | $2550 | Check With Us |
: Cat #: V2293 CAS #: 927885-00-5 Purity ≥ 99%
Description: HS-1793 is a resveratrol analogue which improves the outcome of radiation therapy by enhancing antitumor immunity.
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- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 252.26 |
|---|---|
| Molecular Formula | C16H12O3 |
| CAS No. | 927885-00-5 |
| SMILES Code | OC1=CC=C(C2=CC=C3C=C(O)C=CC3=C2)C(O)=C1 |
| Synonyms | HS 1793; HS1793; HS-1793; |
| Protocol | In Vitro | HS-1793 (0-50 µM; 4 h) inhibits hypoxia-induced HIF-1α protein in MCF-7 and MDA-MB-231 cells unrelated to cell death, downregulates hypoxia-induced VEGF expression, and suppresses hypoxia-induced mRNA expression of VEGF at the transcriptional level. HS-1793 (0-100 µM; 24 h) suppresses proliferation of MCF-7, MDA-MB-231 and HCT116 cells. |
|---|---|---|
| In Vivo | HS-1793 (5 and 10 mg/kg; i.p.; twice a week, 4 weeks) significantly inhibits MDA-MB-231 xenograft tumor growth and in a dose-dependent manner and relatively hampers angiogenesis with non-toxicity. |
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 3.9642 mL | 19.8208 mL | 39.6416 mL | 79.2833 mL |
| 5mM | 0.7928 mL | 3.9642 mL | 7.9283 mL | 15.8567 mL |
| 10mM | 0.3964 mL | 1.9821 mL | 3.9642 mL | 7.9283 mL |
| 20mM | 0.1982 mL | 0.9910 mL | 1.9821 mL | 3.9642 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.