Diatrizoate sodium

This product is for research use only, not for human use. We do not sell to patients.

Diatrizoate sodium
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
500mg$400Check With Us
1g$600Check With Us
5g$1515Check With Us

Cat #: V5946 CAS #: 737-31-5 Purity ≥ 98%

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Molecular Weight (MW)635.90
Molecular FormulaC11H8I3N2NaO4
CAS No.737-31-5
SMILES CodeCC(Nc1c(I)c(C([O-])=O)c(I)c(NC(C)=O)c1I)=O.[Na+]
SynonymsDiatrizoate sodium; Hypaque; MD-50; MD 50; MD50; Triombrin; Urovist Sodium;
ProtocolIn VitroHK-2 cells are exposed to 0-30 mg I/mL Sodium diatrizoate (Diatrizoic acid sodium salt) or vehicle for 2-24 h. MTT and trypan blue exclusion indicate a decrease in mitochondrial and cell viability within 2 and 24 h, respectively.
In VivoSodium diatrizoate is an iodinated radiocontrast agent. Histological examination of rat lung tissue shows no acute toxicity or inflammation after insufflation of Sodium diatrizoate nanoparticle agglomerates. Sodium diatrizoate nanoparticle agglomerates offers a promising radiocontrast agent for safe and effective lung visualization.
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM1.5726 mL7.8629 mL15.7257 mL31.4515 mL
5mM0.3145 mL1.5726 mL3.1451 mL6.2903 mL
10mM0.1573 mL0.7863 mL1.5726 mL3.1451 mL
20mM0.0786 mL0.3931 mL0.7863 mL1.5726 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.