Taurochenodeoxycholic acid sodium salt
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 500mg | $400 | Check With Us |
| 1g | $650 | Check With Us |
| 5g | $1645 | Check With Us |
: Cat #: V38710 CAS #: 6009-98-9 Purity ≥ 99%
Description: Taurochenodeoxycholic acid sodium, the sodium salt of Taurochenodeoxycholic acid, is a naturally occuring bile salt produced in the liver of animals/humans used as a detergent for the solubilization of lipids and membrane-bound proteins.
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| Molecular Weight (MW) | 521.69 |
|---|---|
| Molecular Formula | C26H44NNaO6S |
| CAS No. | 6009-98-9 |
| Synonyms | Taurochenodeoxycholic acid sodium salt; |
| Protocol | In Vitro | Taurochenodeoxycholic acid (12-Deoxycholyltaurine) sodium dramatically improves the apoptosis rate of NR8383 cells in a concentration-dependent manner. In the meantime, Taurochenodeoxycholic acid sodium significantly augments PKC mRNA levels, activities and increases JNK, caspase-3 and caspase-8 mRNA expression levels, activities. |
|---|---|---|
| In Vivo | Taurochenodeoxycholic acid (12-Deoxycholyltaurine; TCDCA; 0.05, 0.1g/kg) sodium decreases the pulmonary coefficient in the model mice and reduces the pathological damages on their lungs; it can decrease the expression levels of TNF-α and TIMP-2 in pulmonary tissues in the pulmonary fibrosis mice and has no significant effects on MMP2. |
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 1.9168 mL | 9.5842 mL | 19.1685 mL | 38.3369 mL |
| 5mM | 0.3834 mL | 1.9168 mL | 3.8337 mL | 7.6674 mL |
| 10mM | 0.1917 mL | 0.9584 mL | 1.9168 mL | 3.8337 mL |
| 20mM | 0.0958 mL | 0.4792 mL | 0.9584 mL | 1.9168 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.