(S)-Tipifarnib

This product is for research use only, not for human use. We do not sell to patients.

(S)-Tipifarnib
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
100mg$1550Check With Us
250mg$2350Check With Us
500mg$3525Check With Us

Cat #: V6027 CAS #: 192185-71-0 Purity ≥ 99%

Description: (S)-Tipifarnib is an inactive enantiomer of Tipifarnib to be used as a negative control.

References: Kraus JM, et al. Rational modification of a candidate cancer drug for use against Chagas disease. J Med Chem. 2009 Mar 26;52(6):1639-47.

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Molecular Weight (MW)489.40
Molecular FormulaC27H22Cl2N4O
CAS No.192185-71-0
SMILES CodeO=C1N(C)C2=C(C=C([C@](C3=CC=C(Cl)C=C3)(N)C4=CN=CN4C)C=C2)C(C5=CC=CC(Cl)=C5)=C1
Synonyms(S)-Zarnestra; (S)-Tipifarnib
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.0433 mL10.2166 mL20.4332 mL40.8664 mL
5mM0.4087 mL2.0433 mL4.0866 mL8.1733 mL
10mM0.2043 mL1.0217 mL2.0433 mL4.0866 mL
20mM0.1022 mL0.5108 mL1.0217 mL2.0433 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.