NSC 146109 HCl
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 500mg | $1250 | Check With Us |
| 1g | $1950 | Check With Us |
| 5g | $4935 | Check With Us |
: Cat #: V5034 CAS #: 59474-01-0 Purity ≥ 98%
Description: NSC 146109 (NSC-146109) HCl, the hydrochloride salt of NSC-146109, is a novel and potent small-molecule p53 activator that targets MDMX, it has the potential in treating breast cancer.
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- Physicochemical and Storage Information
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- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 316.85 |
|---|---|
| Molecular Formula | C17H17ClN2S |
| CAS No. | 59474-01-0 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| SMILES Code | NC(SCC1=C2C=CC=CC2=C(C)C3=CC=CC=C13)=N.[H]Cl |
| Synonyms | XI011; NSC 146109 HCl; NSC146109; NSC146109; XI-011 HCl; XI-011 hydrochloride; XI-011; XI011; XI011; |
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 3.1561 mL | 15.7803 mL | 31.5607 mL | 63.1214 mL |
| 5mM | 0.6312 mL | 3.1561 mL | 6.3121 mL | 12.6243 mL |
| 10mM | 0.3156 mL | 1.5780 mL | 3.1561 mL | 6.3121 mL |
| 20mM | 0.1578 mL | 0.7890 mL | 1.5780 mL | 3.1561 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
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Concentration
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Volume
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Molecular Weight*
The dilution calculator equation
Concentration(start)
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Volume(start)
=
Concentration(final)
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Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
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Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.