Tenovin-3

This product is for research use only, not for human use. We do not sell to patients.

Tenovin-3
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
100mg$1250Check With Us
250mg$2250Check With Us
500mg$3375Check With Us

Cat #: V3038 CAS #: 1011301-27-1 Purity ≥ 98%

Description: Tenovin-3 is a small molecule activator of p53 transcriptional activity and an inhibitor of sirtuin.

References: Lain S, et al. Discovery, in vivo activity, and mechanism of action of a small-molecule p53 activator. Cancer Cell. 2008 May;13(5):454-63.

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Product Promise

Promise
Molecular Weight (MW)327.44
Molecular FormulaC18H21N3OS
CAS No.1011301-27-1
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
Solubility In VitroDMSO: ≥ 31 mg/mLr
Water: <1 mg/mLr
Ethanol: <1 mg/mL
SMILES CodeCC(C)(C)C1=CC=C(C(NC(NC2=CC=C(N)C=C2)=S)=O)C=C1
SynonymsTenovin-3; Tenovin 3; Tenovin3
ProtocolIn Vitro (In Vitro) Tenovin-3 downregulates both P-FAK and P-Src.
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM3.0540 mL15.2700 mL30.5399 mL61.0799 mL
5mM0.6108 mL3.0540 mL6.1080 mL12.2160 mL
10mM0.3054 mL1.5270 mL3.0540 mL6.1080 mL
20mM0.1527 mL0.7635 mL1.5270 mL3.0540 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.