7-epi-Taxol

This product is for research use only, not for human use. We do not sell to patients.

7-epi-Taxol
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Size Price Stock
500mg$1100Check With Us
1g$1850Check With Us
5g$4995Check With Us

Cat #: V34036 CAS #: 105454-04-4 Purity ≥ 99%

Description: 7-epi-Taxol, the epimer of taxol (paclitaxel), is a major and active metabolite of taxol isolated from Taxus brevifolia with comparable anticancr/antitubulin activity to that of paclitaxek/taxol.

References: Ringel I, et al. Taxol is converted to 7-epitaxol, a biologically active isomer, in cell culture medium. J Pharmacol Exp Ther. 1987 Aug;242(2):692-8.

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Molecular Weight (MW)853.91
Molecular FormulaC47H51NO14
CAS No.105454-04-4
ProtocolIn Vitro 7-epi-Taxol has activity comparable to that of taxol on cell replication, microtubule bundle formation and in vitro microtubule polymerization
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM1.1711 mL5.8554 mL11.7108 mL23.4217 mL
5mM0.2342 mL1.1711 mL2.3422 mL4.6843 mL
10mM0.1171 mL0.5855 mL1.1711 mL2.3422 mL
20mM0.0586 mL0.2928 mL0.5855 mL1.1711 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
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Volume
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Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.