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5-Nitrobarbituric acid

This product is for research use only, not for human use. We do not sell to patients.

5-Nitrobarbituric acid
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
50g$400To Be Confirmed
100g$650To Be Confirmed
200g$975To Be Confirmed

Cat #: V43333 CAS #: 480-68-2 Purity ≥ 99%

Description: 5-Nitrobarbituric acid is a herpes simplex virus type-1 (HSV-1) inhibitor with an IC50 of 1.7 μM.

References: J V de Julián-Ortiz, et al. Virtual combinatorial syntheses and computational screening of new potential anti-herpes compounds. J Med Chem. 1999 Aug 26;42(17):3308-14.

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Product Promise

Promise
Molecular Weight (MW)173.08
Molecular FormulaC4H3N3O5
CAS No.480-68-2
Synonyms5-Nitrobarbituric acid
ProtocolIn Vitro5-Nitrobarbituric acid can inhibit vero cell growth.
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM5.7777 mL28.8884 mL57.7768 mL115.5535 mL
5mM1.1555 mL5.7777 mL11.5554 mL23.1107 mL
10mM0.5778 mL2.8888 mL5.7777 mL11.5554 mL
20mM0.2889 mL1.4444 mL2.8888 mL5.7777 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.