5-hydroxytryptophan (5-HTP)

This product is for research use only, not for human use. We do not sell to patients.

For small sizes, please check our retail website as below: www.invivochem.com

Size	Price	Stock
1g	$250	Check With Us
10g	$1250	Check With Us
20g	$1875	Check With Us

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Cat #: V1985 CAS #: 56-69-9 Purity ≥ 98%

Description: 5-Hydroxytryptophan, also known as 5-HTP and oxitriptan, is a naturally occurring amino acid and chemical precursor in the biosynthesis of the neurotransmitters serotonin (5-HT) and melatonin from tryptophan, which is used for the treatment of depression.

References: Gartside SE, et al. Mediation of ACTH and prolactin responses to 5-HTP by 5-HT2 receptors. Eur J Pharmacol. 1990 Apr 10;179(1-2):103-9.

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Physicochemical and Storage Information
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Related Biological Data
Stock Solution Preparation
Quality Control Documentation

Molecular Weight (MW)	220.23
Molecular Formula	C11H12N2O3
CAS No.	56-69-9
Storage	-20℃ for 3 years in powder formr
Storage	-80℃ for 2 years in solvent
Solubility In Vitro	DMSO: > 10 mMr
	Water: NAr
	Ethanol: NA
Synonyms	5-HTP; DL-5-Hydroxytryptophan

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	4.5407 mL	22.7035 mL	45.4071 mL	90.8141 mL
5mM	0.9081 mL	4.5407 mL	9.0814 mL	18.1628 mL
10mM	0.4541 mL	2.2704 mL	4.5407 mL	9.0814 mL
20mM	0.2270 mL	1.1352 mL	2.2704 mL	4.5407 mL

Quality Control Documentation	Select Batch Purity ≥ 98% COA MSDS NMR HPLC

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.